Beyond Pharmacotherapy: Lifestyle-Based Strategies for Improving Cardiometabolic Health

Council For At-Risk Academics (CARA) Research Fellow Dr Nataliia Tofan delivers a seminar on their research -

Hypertension and cardiometabolic disease are commonly managed through pharmacological control of clinical targets. However, achieving numerical targets through pharmacotherapy does not always correct underlying molecular abnormalities. My early research in clinical pharmacology examined how blood pressure responses in elderly patients with hypertension and coronary heart disease reflect intermolecular interactions and complex homeostatic shifts. These findings prompted a broader question: how can cardiometabolic health be improved, and adiposity reduced, through modifiable lifestyle factors such as sleep, physical activity and diet?

At Loughborough University, this question has evolved into a research programme investigating how sleep extension affects blood pressure and glucose metabolism, alongside research on the interaction between exercise, appetite regulation, sleep and obesity and its implications for cardiometabolic disease. Together, this work contributes to an evidence-based lifestyle medicine framework aimed at improving cardiometabolic outcomes in addition to or beyond pharmacological management.

Arrivals from 11:45 am for a 12:00 noon start. For those joining in-person, lunch will be served after the seminar from 1:00pm.

This event is hybrid format, please use the required booking button at the bottom of the page to choose either in-person or online attendance.
(Please note that in-person spaces are limited and booking is required, so we can manage numbers for catering and also the space in the seminar room)

By booking a place at this event, attendees agree to behave in a respectful manner such that everyone feels comfortable contributing as they wish. The IAS reserves the right to eject anyone who does not abide by this policy.

IAS seminars are typically recorded, minus any Q&A sessions at the end, again to encourage contributions. The recordings are then uploaded to our website on a Fellows bio page and/or Programme page, along with our IAS YouTube Channel. If you are not able to attend a seminar live, please do still register as we will email everyone who registered to let them know once the recordings are made available.