Dr Andrew Capel BSc, MSc, PhD
Senior Research Associate
Andrew completed his BSc in Chemistry and Sports Science in 2010 at Loughborough University, before undertaking an MSc in Pharmaceutical Science and Medicinal Chemistry in 2011. That year he began a PhD in the Department of Chemistry, researching the use of 3D Printing as a novel method of manufacturing bespoke milli-scale fluidic devices working alongside Dr. Steve Christie. In 2014 he began working as an RA in the School of Sport, Exercise and Health Sciences, researching next-generation bio-hybrid prosthetics alongside Professor Mark Lewis, Professor Russell Harris and Dr. Steve Christie. Since 2017 he has been employed as a senior research associate by the School of Sport, Exercise and Health Sciences, supporting the daily operation and supervision of Prof. Mark Lewis’ (Dean of SSEHS) research group.
Andrews research to date has operated at the interface between chemistry, engineering, and biology and has encompassed a broad spectrum of research projects focussed predominantly around the design and manufacture of “functional” devices, scaffolds and surfaces. Andrew is currently employed as a senior research associate (2017-Current) by the School of Sport, Exercise and Health Sciences (SSEHS) at Loughborough University, supporting the daily operation and supervision of Prof. Mark Lewis’ (Dean of SSEHS) research group. The group research is focussed on the development of tissue engineered models of the musculoskeletal system. Andrew currently focuses his primary research on the development of a mechanically and electrically actuated multi-tissue “joint”. Mechanical and electrical stimulation can drive maturation within musculoskeletal tissues, thus providing a more biomimetic in vitro environment, while recreating the in vivo stimuli required to generate tissue function. Previously he was employed (2015-2017) on an EPSRC funded project (EP/L02067X/1) focussing on the generation of custom biological surfaces and scaffolds that facilitate precise control over cellular growth. His doctoral thesis focused on design and manufacture of continuous flow reactors via the use of 3D printing. Many of the designs generated throughout these projects have been made open-source and are available as part of the Loughborough University Figshare repository (https://figshare.com/search?q=Lboro3Dprinting&searchMode=1).
- UK Nerve Engineering, Engineering Better Health and Dial-A-Molecule
- A. J. Capel, S. Edmondson, S. D. R. Christie, R. D. Goodridge, R. J. Bibb, M.Thurstans (2013) ’Design and Additive Manufacturing for Flow Chemistry’ Lab on a Chip (I.F. 6.00, SJR 2.16).
- T. Monaghan, A. J. Capel, S. D. Christie, R. A. Harris and R. J. Friel (2015)’Solid-state Additive Manufacturing for Metallized Optical Fiber Integration’ Composites, Part A (I.F. 4.51, SJR 1.54).
- A. J. Capel, A. Wright, M. J. Harding, G. W. Weaver, Y. Li, R. A. Harris, S. Edmondson, R. D. Goodridge, S. D. R. Christie (2016)’ 3D Printed Fluidics with Embedded Analytic Functionality for Automated Reaction Optimisation’ Beilstein Journal of Organic Chemistry (I.F. 2.76, SJR 0.93).
- R.P.Rimington, A.J.Capel, S.D.R. Christie, M.P.Lewis (2017) ‘Biocompatible 3D Printed Polymers via Fused Deposition Modelling Direct C2C12 Cellular Phenotype In Vitro’ Lab on a Chip (I.F. 6.00, SJR 2.16).
- M. Pardo-Figuerez, N.R.W. Martin, D.J. Player, A.J.Capel, S.D.R.Christie, M.P.Lewis (2018) ‘Neural and Aneural Regions Generated by the Use of Chemical Surface Coatings’ ACS Biomaterial Science and Engineering (I.F. 4.43, SJR 1.42)
- J.M.Jones, D.J.Player, N.R.W.Martin, A.J.Capel, M.P.Lewis, V.Mudera (2018) ‘An Assessment of Myotube Morphology, Matrix Deformation, and Myogenic mRNA Expression in Custom-built and Commercially Available Engineered Muscle Chamber Configurations’ Frontiers in Physiology (I.F. 3.39, SJR 1.59)
- R.P.Rimington, A.J.Capel, D.J.Player, R.J.Bibb, S.D.R. Christie, M.P.Lewis (2018) ‘Feasibility and Biocompatibility of 3D-Printed Photopolymerized and Laser Sintered Polymers for Neuronal, Myogenic, and Hepatic Cell Types’ Macromolecular Bioscience (I.F.3.85, SJR 1.02)
- M. Pardo-Figuerez, N.R.W. Martin, D.J. Player, P.Roach, S.D.R.Christie, A.J.Capel, M.P.Lewis (2018) ‘Controlled Arrangement of Neuronal Cells on Surfaces Functionalized with Micropatterned Polymer Brushes’ ACS Omega (I.F. N/A, SJR N/A)
- A.J.Capel, R.P.Rimington, M.P.Lewis, S.D.R.Christie (2018) ‘ 3D Printing for Chemical, Pharmaceutical and Biological Applications’ Nature Reviews Chemistry (I.F. N/A, SJR N/A)
- A.J.Capel, R.P.Rimington, J.W.Fleming, D.J.Player, L.A.Baker, M.C.Turner, J.M.Jones, N.R.W. Martin, R.A.Ferguson, V.C.Mudera, M.P.Lewis (2019) ‘Scalable 3D Printed Moulds For Human Tissue Engineered Skeletal Muscle’ Frontiers in Bioengineering and Biotechnology (I.F. N/A, SJR 1.57)
- Y. Liu, D. Maradze, A.J.Capel, N.R.W.Martin, M.P.Lewis, Y.Zheng (2019) ‘In Vitro Investigation of Cellular Effects of Magnesium and Magnesium-Calcium Alloy Corrosion Products on Skeletal Muscle Regeneration’ Journal of Materials Science and Technology (I.F. 3.61, SJR 1.14) – Accepted Manuscript
- E. Mele, A.J.Capel, J.Smith, M.P.Lewis, R.P.Rimington, S.Li, V.Silberschmidt (2019) ‘Polydimethylsiloxane and Poly(ether) Ether Ketone Functionally Graded Composites for Biomedical Applications’ – In Peer Review
- R.P.Rimington, A.J.Capel, R.J.Bibb, S.D.R. Christie, M.P.Lewis (2019) ‘Myogenic Differentiation of Tissue Engineered Skeletal Muscle within a 3D Printed Perfusion Bioreactor’ – In Peer Review