School of Mechanical, Electrical and Manufacturing Engineering

Staff

Dr Sijung Hu MSc, PhD, MSPIE, SMIEEE

Photo of Dr Sijung Hu

Reader in Biomedical Engineering

Background

After being awarded a PhD at Loughborough University in 2000, Sijung was invited to join Kalibrant Ltd as a Senior Scientist and Project Leader for R&D in vitro diagnostics.

Sijung joined the Wolfson School of Mechanical, Electrical and Manufacturing Engineering, Loughborough University as a research fellow in 2002 for Health Technology Exploitation.

Since 2006, Sijung has been Senior Research Fellow and Leader of the Photonics Engineering & Health Technology Research Group, and ”CREATED TWO NEW FIELDS OF ENGINEERING RESEARCH::

a) Opto-physiological Modeling and Monitoring and;

b) Multiplexed Point-of-care testing instrumentation.

Opto-physiological Modeling and Monitoring (OPM) is to study how light interacts within biological tissue, where the optical properties of the latter reflect the mechanical, physical and biochemical functions of the living organism. Consolidating Optics/Tissue Optics, (µ)electronics and algorithms into biomedical electronic systems,  at component and systems levels, together with a team approach to problem solving is to allows for a clear and rapid progression from fundamental research ideas to engineering realisation.

Multiplexed Point-of-care testing instrumentation (mPOCT) is to research how effectively and simultaneously determine different assays, automate sample feeding, allocation, incubation, detection and rejection. Also, telemedicine is also included in mPOCT with self-calibration and secure clinical date transmission.

Links:

Career summary

  • Senior Research Fellow, Leader for Photonics Engineering and Health Technology Research Group, Loughborough University, UK,  09/2006-date

Roles: Health technology research initiatives and strategies; Fund bidding, The research group activity management including meetings, seminars and research orientations; PhD research supervision, Health technology innovation; Biomedical engineering verification and clinical validation; Coordination with interdisciplinary expertise within the campus; Collaboration with healthcare partners across academics and industrials and national and international.

  • Research Fellow for photonics engineering, Loughborough University, UK, 06/02 – 08/2006

Roles: Research in photonics based non-invasive physiological monitoring, i.e. pulse rate variability analysis; non-invasive venous oximetry (Venox), in-line pulmonary drug assessment; imaging oxygen saturation mapping (OxiMap); Health technology exploitation with two spin-outs, i.e. Dialog Devices and VariDose. 

  • Chief Scientist/Project Leader, Kalibrant Ltd, UK, 01/1999 - 04/2002

Roles: R&D in vitro diagnostic technology for variety of multiplex fluorescence detection systems and point-of-care testing (POCT) instruments; organisation of technology seminars; promotion of R&D outcomes to customers.

  • Research Scientist, Colt International Limited, UK. 02/1994 - 02/1995

Roles: Gas chromatography and spectrophotometry for Volatile Organic Compound (VOC) analysis; VOC testing methods and validation with certificated labs; Development of rapid thermal desorption device for VOC screening.

International and national

International – visiting professor, invited consultant, PhD examiner

  • Independent Assessor and Internal Examiner for PhD students, Loughborough University, 2015, 2016.
  • New generation Opto-Electronic Patch Sensor (OEPS): CareLight has highlighted LU innovative opto-physiological interaction research in Atlas of Science (http://atlasofscience.org/tag/carelight/), 2015.
  • Nomination of the translation research award forWearable opto-physiological sensor based patch sensor research work in BiOS SPIE 2014.
  • Opto-physiological modelling (OPM) was highlighted as a milestone in Pulse Oximetry worldwide by Drexel University 2008 (www.pages.drexel.edu/~kmg462/currentresearch.html).  
  • LU imaging photoplethysmography was appreciated in Future Emergency Care (TM2011-216145, https://ston.jsc.nasa.gov/collections/trs/_techrep/TM-2011-216145.pdf).
  • Chair and internal examiner of PhD Examination Board, Loughborough University, 2013, 2016.
  • Visiting Professorship of Biomedical Engineering, Shanghai Jiao Tong University, 2009 – current. Research capacity: 17 of top 20 universities worldwide and 53 of top 100. Roles: Biophotonics Research and Innovation.
  • Invited PhD Examiner, one of key members of International Exam Board, Shanghai Jiao Tong University, China, 05/2012. Roles: interview with PhD researchers through their thesis.
  • Invited Consultant for regional High Education Institutions (HEIs) collaboration with Chinese HEIs, 2007-2008, Role: Generated UK East Midland China Strategic Plan 2007—2012.
  • Invited Coordinator, Department of Health (DoH International), British Government, 2005-2007, Shanghai International Medical Zone. Role: Coordination of British Health Technology Innovation & joint research activities.
  • Invited Senior Consultant, Shanghai Pudong Association for Science and Technology (SPAST) 2004 –current. Top 400 multinational enterprises in Science Zone. Roles: Science and Technology Collaboration with overseas partners. 

International – conference chair and coordinator

  • Chair of International conference for Advanced Manufacturing for Multifunctional Miniaturised Devices (ICAM3D Conference, Loughborough) 3rd – 4th June 2015
  • Chair of Medical and Biomedical Imaging Section, The 2008 International Conference on BioMedical Engineering and Informatics (BMEI’08), Sanya, China, 05/2008.
  • Chair and Co-ordinator of International Biomedical Engineering Workshop, UK-China Science Network, Loughborough, 06/2006.

International – invited keynotes

  • “A high-performance biometric signal and imaging processing method to reveal blood perfusion towards 3D oxygen saturation mapping”, BiOS Photonics West, SPIE, San Francisco, USA 4th Feb 2014.
  • "Recent Advances in non-contact Opto-physiological monitoring techniques for human metrics" in 2nd International Conference and Exhibition on Biometrics and Biostatistics (Biometrics-2013), Chicago, USA June 2013.
  • in vivo and in vitro Point-of-care Testing instrumentation”, The University of Shanghai for Science and Technology, and Shanghai University on 23rd and 28th July 2012, separately.
  • “Electrically conductive adhesive enable to manufacture high performance patch probe for non-invasive physiological assessment”, International Conference in Advanced Manufacturing for Multifunctional Miniaturised Device (M6), Huazhoung University of Science Technology, Wuhan, China, 21st and 22nd May 2012.
  •  Detection of physiological changes after exercise via a remote opto-physiological imaging system”, BiOS Photonics West, SPIE, San Francisco, USA 21-26th Jan., 2011.
  • A study of opto-physiological modeling to quantify tissue absorbance in imaging photoplethysmography”, IEEE EMBC 32, Buenos Areas, Argentina, 2010.
  • “Development of effective photoplethysmographic measurement techniques: from contact to non-contact and from point to imaging”, IEEE EMBC 31, Minneapolis, USA, 2009.
  • “A remote approach to measure blood perfusion from human face”, BiOS, Photonics West, San Jose California, USA 2009.
  • “Development of a Remote Photoplethysmographic Technique for Human Biometrics”, BiOS, Photonics West, San Jose California, USA 2009.
  • Feasibility study of imaging Photoplethysmography”, International Conference on BioMedical Engineering and Informatics (BMEI’08), Sanya, China 05/2008.
  • Photonics Engineering and Health Technology Today and Tomorrow”, UK Mission to New Zealand, Health Innovation, Auckland, New Zealand, 3rd April 2008.
  • “Remote simultaneous dual wavelength imaging photoplethysmography: a further step towards 3-D mapping of skin blood microcirculation”, BiOS, Photonics West, San Jose California, USA 2008.
  • Development and Application of Forthcoming Photoplethysmographic Platform”, International Biomedical Engineering Workshop, UK-China Science Network, Loughborough, 6-9th June 2006.
  • Biophotonics Engineering and Innovation”, Optoelectronic Industry and International Forum on Intellectual Property 2005 in Shanghai, China.

National – invited keynotes

  • in vivo and in vitro Point-of-care Testing Research”, 3rd Research Conference at School of Electronic, Electrical and Systems Engineering, Loughborough University, 16th-17th April 2014
  • in-vivo and in-vitro Point-of-care Testing instrumentation, principle, functionality, systems, manufacturing”, The University of Sheffield, 1st March 2012.
  • “Effective photoplethysmographic measurement techniques”, UKIERI Workshop on Mobile communications to improve monitoring of heart disease and diabetes, Loughborough, 7th July 2010
  • Loughborough University Opto-physiological Monitoring”, Applied Optics Seminars, The University of Nottingham, 22 April 2009.
  • “Comparison of pulse interval in contact and non-contact photoplethysmography” ESC DIVISION RESEARCH, IEEE, Loughborough University 2005.

Industry activity 

  • 1999 - 2002 Senior Scientist /projector leader, Kalibrant Limited. in vitrodiagnostic (IVD) instrumentation development specialising in multi-wavelength fluorescence detection system coupling CCD, optical fibre, various laser sources.
  • 1994 - 1995 Research scientist, Colt International Limited, Thermal Desorption system and auto-control for ultra trace analysis with GC and spectrophotometer  for air pollution abatement including volatile organic compounds (VOC) monitoring.
  • 1982 -1992 Research Scientist and engineer, Test Centre of Chemical Fibre, Ministry of Textile Industrial, China. Substantial International Standards (ISO) drafting and modification for chemical and biochemical products analysis utilising HPLC, Spectrophotometer, ICP-MS etc. and also biosensor and instrumentation development.

Professional activities

Professional committee member:

  • Senior Member of the Institute of Electrical and Electronics Engineers (SMIEEE), 2002- present.
  • Member of IEEE in Medicine and Biology Society (MIEEE MBS), 2002 – present.
  • Senior Member of International Society for Optical Engineering, (SMSPIE), 1998 – present.
  • Member of Technical Committee, International Convention on Rehabilitation Engineering and Assistive Technology (i-CREATe), 2010 – present.
  • Fellow of High Education Academia2016 - present.

Invited and principal reviewer for:

  • Scientific Reports - Nature
  • Annals Biomed Eng
  • Applied Optics
  • EURASIP J Adv Signal Processing
  • IEEE Trans Biomed Eng
  • IEEE Trans Biomed Circuit System
  • J Biomed Optic
  • Applied Spectroscopy
  • J Optics A: Pure Applied Optics
  • J Biophotonics
  • J Clin Monitor Comput
  • J Healthcare Eng
  • Measurement
  • Med Eng Physics
  • Medical Eng Physics
  • J Rehabilitation Research and Development
  • J Med Biolog Eng
  • Physiology Behaviour
  • Measurement Sci Tech
  • Optical Express
  • Sensors
  • Biosensors
  • Biomed Optics Express
  • Physiol Measure
  • Biomed Physics Eng Express (BPEX)
  • IEEE Biomed Eng Conf Proc
  • Opto-Electronics Review
  • Editorial board member of Austin J Biomed Eng 

Research interests 

  • Tissue Optics, Sensing for Physiological Monitoring & Assessment
  • Signal/imaging Processing
  • Microfluidics based Lab-on-a chip & MEMS for in vitro Diagnosis POCT
  • Non-contact and Wearable optoelectronic sensor for in vivo
  • Optoelectronic Systems for health screening, monitoring, diagnosis and assessment
  • Health Technology Innovation

Current research projects

  •  “Carelight commercialisation and partnership with Haiyuntech (www.haiyuntech.co.uk)”, Carelight Patented Tech Licensing and Consultation, £500k per year until 2026, S Hu, 06/2016- 07/2026
  • “Real-time physiological monitoring in next generation eHealth network”, £70k, PhD Research, Saudi Arabian Cultural Bureau, 2016 – 2019
  • “Physiological monitoring electronics”, £1k, Visiting Academic project in LU, Shanghai University, 09/2016-08/2017
  • “Carelight: a novel way to measure vital signs to a high clinical standard as a simple wearable patch sensor”, EPSRC-EPG, S Hu, £11,000 03/2016 – 03/2017.
  • “Functional cotton fabrics with durable sensing ability”, granted by Cotton Cooperation, USA to J Sheng (DMU), S Hu (LU) and C Hunt (NPL, UK). $50,000, 01/2015 – 03/2016, will be followed up with $60,000 until the end of 2017.
  • Intelligent, adaptable electronics for healthcare and wellbeing mini-CDT”, five PhD Studentships, £200k, CI, The Loughborough Doctoral College, 10/2014 –10/2018
  • Imaging photoplethysmography (iPPG) for real-time retinal blood perfusion assessment”, PhD Research, £60k, Majlis Amanah MARA, Malaysia, 01/2014 – 01/2017

Completed research projects

  • “Development and testing of commercial prototypes for wearable opto-electronic patch sensor”, £15.145k, PI, Enterprise Project Grant of Loughborough University, 10/2014 – 07/2015
  • “Opto-physiological measurement”, £90k, PI, Enterprise Project Grant of Loughborough University, 2013 – 14
  • “Development of Real-time opto-physiological image processing platform”, £5k, PI, LU-EPSRC Pathways to Impact fund, 01/2013 – 03/2013
  • “Opto-physiological measurement”, £64.2k, PI, Enterprise Project Grant of Loughborough University, 2013 – 14
  • “Micro-Multi-Material Manufacturing to Enable Multifunctional Miniaturised Devices”, £500k, CI, FP7-PEOPLE-2010-IRSES, No 269113 – Acronym: M6, 04/2011 – 12/2015
  • “Opto-physiological imaging: from modelling to engineering solution”, £10k, PI, LU-EPSRC Shaping Capability Fund, 07/2012 – 09/2012, Outcome: Generated a non-contact vascular assessment platform.
  • “Rapid Windscreen Defrosting System for Motor Vehicle”, £50k, PI, Nissan 10/2011 – 01/2012, Outcome: A Technical, Report for Nissan European Research Centre.
  • “Non contact measurement of aortic compliance”, £100k, CI, NIHR Grant No. II-FS-0109-11005, 05/09- 10/11, Outcome: Ground-breaking Imaging photoplethysmography System with full functionalities to access human vascular status in London Chester Hospital.
  • “Imaging photoplethysmography towards remote physiological assessment”, £50k, PI, Joint PhD, Loughborough University and Shanghai Jiao Tong University, Scholarship Award. 11/2009-12/2011, Outcomes: PhD completion within 24 months with three top leading journal papers.
  • “Optical Turbidity Measurement for Existing Assays”, £60k, PI, Shanghai Upper Bio-Tech Pharma “02/2009-02/2010, Outcomes: Three Technical Reports.
  • “Design and Testing of a Photoplethysmographic Probe for Monitoring Large Arterial Compliance in Critical Care Patients”, £3k, CI, MRC No: G0502256/77947, 03/2009-08/2009, Outcomes: Provided four reflection photoplethysmographic probes for clinical trials and led i4i NHIR fund bidding.
  • “Venous Oximetry” and “Imaging Photoplethysmography”, £60,693, PI, East Midland Innovation Fellowship, HIRF 361, HIRF 461, 09/2007 – 04/2009, Outcomes: Commercial exploitation of Venous Oximetry (Venox); Imaging of Local Blood Oxygenation, (WO 2009/030934 A3), 12 March 2009.
  • “Non-contact reflection photoplethysmography towards effective human physiological monitoring”, £35k, Loughborough University and Shanghai Jiao Tong University, Joint PhD Scholarship Award, 12/2007-07/2009, Outcomes: PhD completion within 24 months with five leading academic journal papers, four peer review conference proceeding papers, and the best poster in Photons 2008.
  • “International Conference Grant”, £1k, PI, Royal Academy of Engineering, 05/2008, The 2008 International Conference on BioMedical Engineering and Informatics (BMEI’08), Sanya, China,.
  • “International Conference Grant”, £1.2k, Royal Society, 01/2008, BiOS, SPIE, 2008, San Jose, USA, Royal Society, Outcomes: Two peer review proceeding papers.
  • “Imaging Photoplethysmography”, £12k, CI, EPSRC Platform: Pioneering new optical techniques, instruments and processes, GR/T25040/01, 05/2006-07/2008, Outcome: One peer review proceeding paper.
  • “International Conference Grant”, £1k, Royal Academy of Engineering, 12/2006, BiOS SPIE, 2007, San Jose, USA, Outcome: One peer review proceeding paper.
  • “Multi-time gating approach, real time medical and biomedical signal and imagine processing”, £6k, PI, Loughborough University Enterprise Limited, 07/2006. Outcome: One patent filed. 
  • “Pulse rate variability measurement for brain ischaemia and diabetes assessment”, £12k, PI, Royal Society and NSFC Joint project, 2005/R1-JP, 07/2005-08/2007,  Outcomes: Joint biomedical engineering Research with singed MOU and agreement, one leading academic journal paper and three peer review conference proceeding papers.
  • “International Biomedical Engineering Workshop, UK-China Science Network”, £20k, PI, Royal Society, JEB/Follow-Up Networks, 06/2006, Loughborough University, AstraZeneca, DaVinci Health Network, Outcomes: one workshop proceeding consisting 26 contributed papers, 12 keynote speakers (two IEEE Fellows, one Fellow of UN consultant for healthand over 100 attendees of senior clinicians, academic researchers, and industrials.
  • “International Conference Grant”, £2k, Royal Society, 08/2005, IEEE EMBS05, Shanghai, Outcome: One peer review proceeding paper.
  • “Technology Innovation and Management”, Chevening Scholarship £25k, PI, London Business School, 2002-2003, Tech Innovation, Effective presentation, Fund bidding, Business Plan and Strategy, and Finance.
  • “VariDose: Development and Commercialisation for in-line Pulmonary Drug Assessment”, £1.5k PI, EPSRC Business Competition, 10/2002, Outcome: Small Business Competition (2nd round).

Current PhD supervision 

  • “New Generation of Opto-Electronic Patch Sensor to enable effective human vital signs monitoring for healthcare, personal health monitoring during physical activity and sports performance”, Panagiotis Blanos (2017 – 2020), Sponsored by EPSRC.
  • “Real-time physiological monitoring in next generation eHealth network”, Samah Alharbi (2016-19), sponsored by Saudi Arabian Cultural Bureau.
  • “Smart miniaturisation and holistic integration of high performance POCT device”, Hannah Robins (2013 – 16), sponsored by Loughborough University.
  • “Imaging photoplethysmography (iPPG) for real-time retinal blood perfusion assessment”, Harnani Hassan (2014 – 17), sponsored by Majlis Amanah MARA, Malaysia.
  • “A multidisciplinary engineering approach to effectively reveal patho-physiological status”, Dmitry Iakovlev (2014-17), sponsored by Loughborough University.
  • “Development of Multi-sensor Integration Platform to Support Investigations in Exercise Training”, Samuel Adema, (2014-17), sponsored by Loughborough University. Co-Supervisor.

Completed and awarded PhD

  • “A Reflectance Patch Pulse Oximeter for Remote Physiological Monitoring”,Abdullah Alzahrani (2012-16), sponsored by Saudi Arabian Cultural Bureau, Principal Supervisor.
  • “High performance illumination for cost-effective imaging pulse oximetry”, Ryan Imms (2010-15), sponsored by Loughborough University, Principal Supervisor.
  • “Microelectronics architecture for real-time biomedical imaging processing”, Dave Stevens (2008-13), sponsored by Loughborough University, Co-supervisor.
  • “Multiscale Modelling of Epithelial to Mesenchymal Transition”, Tariq Abdulla (2009 -2013), sponsored by Loughborough University, Co-supervisor.
  • “Imaging photoplethysmography towards remote physiological assessment”, Yu Sun (2009-11), sponsored by Loughborough University and Shanghai Jiao Tong University, Principal Supervisor.
  • “Non-contact reflection photoplethysmography towards effective human physiological monitoring”, Ping Shi (2007–09) sponsored by Loughborough University and Shanghai Jiao Tong University, Principal Supervisor.
  • “Opto-physiological modelling for imaging photoplethysmography” Jia Zheng (2006-09), sponsored by Loughborough University, Principal Supervisor.
  • “Feasibility of Non-contact photoplethysmography”, Peck Yeng Sharon Cheang, (2002-07), sponsored by Loughborough University, Principal Supervisor.
  • “Opto-physiological modelling of pulse oximetry”, Vince Azorin-Peris (2005-08), sponsored by the EPSRC optical platform grant, Principal Supervisor.
  • “Development and Validation of Venous Oximetry”, sponsored by Loughborough University Angelos Echiadis (2003-07), Principal Supervisor.

On-gong and completed visiting scholar supervision 

  • “Physiological monitoring electronics”, Prof Liangwei Yan, Shanghai University, 09/2016-08/2017.
  • “Systematic control for non-invasive peripheral vascular assessment system”, Prof Anhua Dong, Henan Polytechnic University, China (2007).
  • “Postural changes on lower limb blood volume, detected with non-invasive photoplethysmography”, Prof Shangzhi Xin, University of Shanghai for Science and Technology, China (2005-06).
  • “Pulse rate variability using photoplethysmography”, Prof Yihong Qiu, Shanghai Jiao Tong University, China, 07-09/2004, Royal Society income visiting scholar scheme.

International - Research collaboration with academics and industrials

  • Carelight Sensor Technology and Application (2016 – present), Haiyuantech Co., China, www.haiyuantech.com.   
  • Opto-electronic sensing device and system (2012- present), Shanghai University, China (www.en.shu.edu.cn).
  • Healthcare Telematics/Home Care,(2012 - presentFraunhofer-Institut Biomedizinische Technik (IBMT), Germany(www.ibmt.fraunhofer.de).
  • Bio-systems integration for Point-of-care Testing, (2011-current), VTT Technical Research Centre of Finland (www.vtt.fi/index.jsp).
  • Rapid manufacturing for point-of-care testing device (2010-present), Huazhong University of Science and Technology (HUST), China (english.hust.edu.cn).
  • in vitro diagnosis Point-of-care Testing with multiplexed assays (2009-present), Biomedical Diagnosis Research Institute, Dublin City University, Ireland (www.bdi.ie).
  • High performance fluorescence detection system for in vitro diagnosis Point-of-care Testing, (2009-current) ACREO, Sweden (www.acreo.com).
  • in vitro diagnosis Point-of-care Testing with microfluidics, (2009-present), University of Applied Sciences Kaiserlautern, Germany (www.fh-kl.de/fh/intl.html).
  • in-vitro diagnosis Point-of-care Testing with Lab-on-a chip cartridge, (2009-present),University of Milan, Italy (www.unimi.it).  
  • Biomedical Engineering for in vivo instrumentation and signal processing, (2009 –present), Université Paris-Sud (www.u-psud.fr). 
  • in vivo and in vitro vascular health assessment, (2008- present),Philips Health Research (www.philipsresearch.com).
  • Health Technology Research (2006-present): University of Shanghai for Science and Technology (www.usst.edu.cn).
  • Health Technology Transfer and Innovation (2005-current): Shanghai Pudong Association for Science and Technology (www.pdkp.org), one of the biggest Globe Economic Zones.
  • Partnership with the signed MoU (2004 - 2009) and Research Agreements (2006-current): Shanghai Jiao Tong University (Biomedical engineering ranked 1 in China, bme.sjtu.edu.cn/en/ ). 

National – Research collaboration with academics and industrials

  • Optoelectronic sensor and electronics (2016 – present), BPC Electronics LLP (UK) (www.bpc-electronics.com)
  • Rapid Sepsis screening, monitoring and assessment (2016 –present), NHS Birmingham(www.uhb.nhs.uk)
  • Novel Photonics Devices and Applications (2008 – present), The University of Sheffield, (www.shef.ac.uk
  • in vivo physiological imaging for burns blood perfusion assessment, (2007-present),Moor Instruments (www.moorinstruments.com).
  • Biomedical Engineering Research (2006 - present), City University, London, (www.city.ac.uk)
  • Peripheral Vascular Disease Diagnosis (2006-present), Queen Marry, The University of  London, (www.qmul.ac.uk)
  • Photonics engineering research prototyping, (2005 - present), Cambridge Consultant Limited, (www.cambridgeconsultants.com)
  • Cardiovascular disease screening (2003- present), NHS Leicester, (www.leicestershospitals.nhs.uk)

Awards

  • Nominated as the translation research award BiOS SPIE 2014 for Wearable opto-physiological sensor based patch sensor.
  • Joint Biomedical Engineering Research of Award 2013, “Opto-physiological modelling”, Hu, S., Shanghai Jiao Tong University, China
  • Rank 1 of TOP 10 ARTICLES PUBLISHED IN BioMedLib, 2011, “Development of effective photoplethysmographic measurement techniques: from contact to non-contact and from point to imaging”, Hu, S., Azorin Peris V., Echiadis A., Zheng J., Shi, P., Proc. IEEE EMBC 31, 2009, 1: 6550 - 6553.
  • Health Technology Innovation Award 2007, UK, “Development and Application Non-Invasive Venous Oximetry (Venox)”, Hu, S., Spyt, T., Echiadis, A., Da Vinci Health Technology Network UK.

 

Selected publications

Journal papers - (published)

  • “A Multi-Channel Opto-Electronic Sensor to Accurately Monitor Heart Rate against Motion Artefact during Exercise”, Alzahrani, A. Hu, S.*, Azorin-Peris, V., Barrett, L., Esliger, D., Hayes, M., Akbare, S., Achart, J., Kuoch, S., Sensors 2015, 15, 25681-25702; doi:10.3390/s151025681
  • “The response of the autonomic nervous system to passive lower limb movement and gender differences”, Shi, P., Hu, S., Yu, H., Med Biol Eng Comput, 2015, DOI 10.1007/s11517-015-1378-4
  • A Comparison Study of Physiological Monitoring with a Wearable Opto-Electronic Patch Sensor (OEPS) for Motion Reduction”, Alzahrani, A., Hu, S*., Azorin-Peris, V., Biosensors, 5, 288-307 (2015); doi:10.3390/bios5020288
  • Influence of computer work under time pressure on cardiac activity”, Shi, P., Hu, S., Yu, H., Comput Biolog Medi, 58, 40–45 (2015)
  • Opto-physiological modeling applied to photoplethysmographic cardiovascular assessment”, Hu, S.*, Azorin-Peris, V., Zheng, J., Invited Review Paper, J Healthcare Eng. 4 (4), 505-528 (2013).
  • “Non-contact imaging photoplethysmography to effectively access pulse rate variability”, Sun, Y., Hu, S.*, Azorin-Peris, V., Kalawsky, R., Greenwald, S., J Biomed Optic 18(6), 061205 (2013).
  • “The use of ambient light in remote photoplethysmographic systems: a comparison between a high performance camera and a low cost webcam”, Sun, Y., Papin. C., Azorin-Peris, V., Kalawsky, R., Greenwald, S., Hu, S.*, J Biomed Optic., 17(3), 037005 (March 2012).
  • “BioThreads: A Novel VLIW-Based Chip Multiprocessor for Accelerating Biomedical Image Processing Applications”, Stevens, D.; Chouliaras, V.; Azorin-Peris, V.; Zheng, J.; Echiadis, A.; Hu, S.*, Biomed Circ Sys, IEEE Trans., 6(3):257-268 (2012).
  • “Motion-compensated noncontact imaging photoplethysmography to monitor cardiorespiratory status during exercise”, Sun, Y., Hu, S.*, Azorin-Peris, V., Greenwald, S., Chambers, J., Zhu, Y., J Biomed Optic 16(7), 077010 (July 2011).
  • “Innovations towards Personalised Biomedical Photonic Devices”, Summers, R., Hu, S., Measurement and Control, 44(6), pp.175-179, ISSN: 0020-2940.
  • Non-contact Reflection Photoplethysmography towards Effective Human Physiological Monitoring”, Shi, P., Azorin Peris, V., Echiadis, A., Zheng, J., Zhu, Y., Cheang, P. Y. S.,  Hu, S.*, J Med. Biol. Eng. Vol.30 Iss 30 (2010): 161-167
  • “Insight into the dicrotic notch in photoplethysmographic pulses from the finger tip of young adults”, Shi, P.,  Hu, S.*,  Zhu, Y., Zheng, J., Qiu, Y., Cheang, P. Y. S.,  J Med Eng Tech, Vol. 31, Iss 8 (2009), 628 - 633
  • “Analysis of pulse rate variability derived from photoplethysmography with the combination of lagged Poincaré plots and spectral characteristics”, Shi, P., Zhu Y., Allen, J., Hu, S.*, Med Eng. Phys. 31 (2009) 866–871,
  • ''Study on Blood Pulse Photoplethysmography Signal on Toe Under Different Body Posture and Lower Limb Height'', Xin, S., Hou, W., Qian, J., Hu, S., Crabtree, V.P.,  Smith, P.R.,  J  University of Shanghai for Science and Technology, 30(5), November 2008, pp 173-180, ISBN 1609 0985.
  • “Effect of postural changes on lower limb blood volume, detected with non-invasive photoplethysmography”, Zheng, J., Hu, S.*, Xin, S., Crabtree, V., J Med Eng Tech, Vol. 32, Iss 5 (2008), 358 - 364
  • “A Preliminary Attempt to Understand Compatibility of Photoplethysmographic Pulse Rate Variability with Electrocardiogramic Heart Rate Variability", Shi, P., Hu, S*., et al J Med. Biolog. Eng., Vol.28, Iss 4 (2008): 173-180
  • “Detrended Fluctuation Analysis of Pulse Rate Variability Signals of Coronary Patients”, Zhao, H., Qiu, Y., Hu, S., Zhu, Y., Space Med and Medical Eng, Vol. 20, No. 6 (2008), 455-457
  • Non-invasive measurement of peripheral venous oxygen saturation using a new venous oximetry method: evaluation during bypass in heart surgery”, Echiadis, A. S., Crabtree, V. P., Bence, J., Hadjinikolaou, L., Alexiou, C., Spyt, T. J., Hu, S., , Physiol. Meas. Vol.28 (2007) 897–911
  • “Investigation of Blood Pulse PPG Signal Regulation on Toe Effect of Body Posture and Lower Limb Height”, Xin, S., Hu, S.*, Crabtree, V. P.,  Zheng, J., Azorin-Peris, V., Echiadis, A., and Smith, P. R., J Biomedicine and Biotechnology, Vol. 8 (2007)  No. 6. 916-920
  • “A Monte Carlo Platform for the Optical Modelling of Pulse Oximetry”, Azorin-Peris, V., Hu, S.*, Smith, P. R, Applied Physics Letters, SPIE, Vol.6446 (2007), pp.64460T
  • “Complex character analysis of Heart Rate Variability following brain asphyxia”, Cai, Y., Qiu, Y.,H., Wei, L., Zhang, W., Wang, Z., Jiang, D., Hu, S., Smith, P. R., Crabtree, V. P., Tong, S.B., Thankor, N., Zhu, Y., Med  Eng. Phys. 28 (2006) 297–303
  • “A Compact Long wavelength Fluorescence Detection System and its Application to Flow Injection Immunoassay”Hu, S. J, French, M.T. Palmer, P. A., Evens, M., Zhou, S. M., Sarpara, G. H., Miller, J. N., Analytica Chimica Acta (2002), ISSN: 0003-2670 Vol: 454 Iss: 1, pp. 31-35
  • A New Long-Wavelength Fluorigenic Substrate for Alkaline Phosphatase; Synthesis and Characterisation” , Sarpara, G. H., Hu, S. J, French, M. T. Miller, J. N., et al Analytical Communications, (1999), Vol. 36, pp.19-20.
  • “Determination of Phloroglucin in Wastewater Using Electrolysis”, Hu, S. J*., Environmental Protection, China, 1988, and was also awarded as an Excellent paper, (1988), No. 11, pp.2–4.
  • Determination of Apparent Colour in Water and Wastewater Using Chromatometry”, Hu, S. J*., in Test Centre of Chemical Fibre, Ministry of Textile Industry, China, (1987), Vol.11, pp.1–10.
  • “Recycling of Silver and Removal of Chromium from CODcr Waste Liquor”, Hu, S. J*., Environmental Protection, China, (1987), No.7, pp.24–25.

Patents published and ownership

  • Opto-Physiological Sensor and Method of Assembly”, Hu, S.,Azorin-Peris, V., UK International Patent Application No: , Granted: GB2524919
  • Medium Throughput in-vitro Diagnostic Methodology and Instrumentation”, Hu, S., Azorin Peris, V., Simpkin, M., CN201110073094.1, Priority date: 11/10/2011, the granted date: 28/02/2013
  • A Multiplex fluorescence and Absorbance Detector”, Hu, S., CN101236153, Priority date: 06/08/2008, and the granted date: 02/2009
  • An Assay Apparatus with Multiple Detectors”, Hu, S. J., et al, PCT WO99/08115, Priority date: 12/8/97, PCT Publication Date: 18/2/99
  • “A Detector”, Hu, S. J., et al PCT WO99/08096, Priority date: 12/8/97, PCT Publication Date: 18/2/99
  • OxiMap: Imaging of Local Blood Oxygenation”, Hu, S., Azorin Peris, V., Echiadis, A., WO 2009/030934 A3, 2009.
  • Venox, non-invasive venous oximeter”, WO 03/063697 A1, Ownership: Hu, S.

 

Conference contributions (peer-reviewed Proceedings)

  • “Integration of a microfluidic chip with multiplexed optical fluorescence detector through anisotropic etching of Si using Tetramethylammonium hydroxide (TMAH)”, Robbins, H., Liu, C.,  Hu, S., Bui T., Aoyagi, M., 6th Electronic System-Integration Technology Conference (ESTC), Grenoble, France , 2016
  • “Noncontact blood perfusion mapping in clinical applications”, Iakovleva, D., Dwyer, V., Hu, S., Silberschmidtb, V., Proc. SPIE. Vol. 9887, 988712, Brussel, Belgium, 2016
  • “A new engineering approach to reveal correlation of physiological change and spontaneous expression from video images”, Yang, F., Hu, S.*, Ma, X., Hassan, H, Wei, D., Proc. SPIE, 9315, 93150M, BiOS, Photonics West, San Francisco, USA, 2015
  • “A dynamic opto-physiological model to effectively interpret retinal microvascular circulation”,  Hassan, H., Hu, S*., Dwyer, M. V., Proc. SPIE, 9315, 931505, BiOS, Photonics West, San Francisco, USA, 2015.
  • “An scalable engineering approach to improve performance of a miniaturized optical detection system for in vitro point-of-care testing”, Robbins, H., Hu, S.*, Liu, C., Proc. SPIE, 9320, 932007, BiOS, Photonics West, San Francisco, USA, 2015.
  • “Enhancement of absorption and resistance of motion utilizing a multi-channel opto-electronic sensor to effectively monitor physiological signs during sport exercise”, Alzahrani, A., Hu S*., Azorin-Peris, V., Barrett, L., et al., Proc. SPIE 9315, 93150O, BiOS, Photonics West, San Francisco, USA, 2015
  • “A high performance biometric signal and image processing method to reveal blood perfusion towards 3D oxygen saturation mapping”, Imms, R., Hu, S*., Azorin-Peris, V., Tricob, M., Summers, R., Proc. SPIE Vol. 8947 89470X-1, BiOS, Photonics West, San Francisco, USA, 2014
  • “A Novel yet effective motion artefact reduction method for continuous physiological monitoring”, Alzahrani, A., Hu, S.*, Azorin-Peris, V., Kalawsky, R. Design and Quality for Biomedical Technologies VI”, Proc. SPIE Vol. 8936 89360G-8,  BiOS, Photonics West, San Francisco, USA, 2014.
  • “An Effective Solution to Reduce Motion Artefact in New Generation Reflectance Pulse Oximeter”, Alzahrani, A., Hu, S.*,Proc SIECPC-2013, 1 – 5, ieeesplore.ieee.org
  • “Electrically conductive adhesive enable to manufacture high performance patch probe for non-invasive physiological assessment”, Zhang, X., Hu, S.*, Liu, C., Azorin-Peris, V., Imms, R., Proc Electronics System-Integration Tech Conf (ESTC) 2012
  • “The Potential of Internet of m-health Things “m-IoT” for Non-Invasive Glucose level Sensing”, Istepanian, R.S .H., Hu, S.*, Philip, N., Sungoor, A., Proc. IEEE EMBC 33, Boston, Massachusetts USA, August 30 -September 3, 2011, 5264-66
  • “A graph theoretic analysis of cortical functional connectivity of depressed patients on the basis of EEG measurements”, Sun, Y., Hu, S.*, et al., Proc. IEEE EMBC 33, Boston USA, August 30, September 3, 2011, 1419-22.
  • “Comparison of scientific CMOS camera and webcam for monitoring cardiac pulse after exercise”, Sun, Y., Papin. C., Azorin-Peris, V., Greenwald, Hu, S.*, Proc SPIE, 813506 1-7, Photonics SPIE, San Diego, USA 2011.
  • "Innovations towards personalized biophotonic devices", Summers, R., Hu, S., IEEE International Instrumentation and Measurement Technology Conference Hangzhou, China, May 10-12, 2011
  • “Detection of physiological changes after exercise via a remote opto-physiological imaging system”, Sun, Y., Hu, S.*, Azorin-Peris, V., Zheng, J., Chambers, J., Greenwald. S, Proc. SPIE, Vol. 7891, 78910E, 2011
  • “A study of opto-physiological modelling to quantify tissue absorbance in imaging photoplethysmography”, Hu, S.*, Azorin Peris V., Zheng J., Proc. IEEE EMBC 32, 2010, 1: 5776 – 5779
  • “Development of effective photoplethysmographic measurement techniques: from contact to non-contact and from point to imaging”, Hu, S.*, Azorin Peris V., Echiadis A., et al, Proc. IEEE EMBC 31, 2009, 1: 6550 - 6553.
  • “Innovation for Personalization: A Healthcare Case Study”, Summers R., Hu S.*, Echiadis A., MIEEE, Azorin-Peris V., Chouliaras V., Proc. IEEE EMBC 31, Minneapolis, USA, 2009.
  • “A remote approach to measure blood perfusion from the human face”, Zheng, J., Hu, S., * Azorin-Peris, V., Echiadis, A., Shi, P., Chouliaras, V., 7170. 7170-4., Proc. SPIE BiOS, Photonics West, San Jose, USA 2009
  • “Development of a remote photoplenthysmographic technique for human biometrics”, Shi, P., Hu, S.*, Zhu., Y, Zheng, J., Azorin-Peris, V., Echiadis, A., 7169. 7169-41., Proc. SPIE BiOS, Photonics West, San Jose, USA 2009
  • "Real-time VLSI architecture for bio-medical monitoring", Chouliaras, V., Hu, S.*, Azorin-Peris, V., Echiadis, A., Summers, R., Zheng, J., King, I., Proc. ITAB 2008, Shenzhen, China, 2008
  • “Feasibility of imaging photoplethysmography”, Hu, S.*, Zheng, V., Chouliaras, V., Summers, R., Proc. CISP’08 – BMEI’08, Sanya, China, 2008
  • Remote simultaneous dual wavelength imaging photoplethysmography: a further step towards 3-D mapping of skin blood microcirculation”, Zheng, J., Hu, S.*, Azorin-Peris, V., Echiadis, A., Chouliaras, V., Summers, R., Appl. Phys. Lett. 0003-6951, Proc. of SPIE Vol. 6850 68500S-1, Photonics West, San Jose, USA, 2008.
  • “Validation of a Monte Carlo Platform for the Optical Modelling of Pulse Oximetry”, Azorin-Peris, V., Hu, S.*, Proc 3rd Ann Meeting on Optical Sensors in Physiological Measurements; London, May 2007
  • “The preliminary investigation of imaging photoplethysmographic system”, Zheng, J., Hu, S.*, Proc 3rd Ann Meeting on Optical Sensors in Physiological Measurements; London, May 2007
  • “A Monte Carlo Platform for the Optical Modelling of Pulse Oximetry”, Azorin-Peris, V., Hu, S.*, Smith, P. R., Proc BiOS, SPIE 2007, 6446,64460T, Photonics West, San Jose, USA, 2007
  • “Development and Application of Forthcoming Photoplethysmographic Platform”, Hu, S*., Proc Int’l Biomedical Engineering Workshop, UK-China Science Network, Loughborough, 06/2006
  • “Pulse rate variability: a framework for movement artefact investigations”, Zheng, J., Hu, S.*, Smith, R. P., Proc Int’l Biomedical Engineering Workshop, UK-China Science Network Loughborough, 06/2006
  • “Venox: Non-invasive Venous Oximetry”, Echiadis, A., Spyt, T., Crabtree, P.V., Smith, R. P., Hu, S., Proc Int’l Biomedical Engineering Workshop, UK-China Science Network, Loughborough, 06/2006
  • “Artefact Reduction in Pulse Oximetry”, Azorin-Peris, V., Hu, S.*, Smith, P. R., Proc Int’l Biomedical Engineering Workshop, UK-China Science Network, Loughborough, 06/2006
  • Development of non-invasive photoplethysmography to assess lower limb peripheral perfusion”, Hu, S.*, Zheng, J., Xin, S., Crabtree, V. P., Smith, P. R., Proc Photon 06, Manchester 2006
  • Poincaré plot analysis of pulse intervals extracted from non-contact photoplethysmography”, Hu, S*., Qiu, H., Cai, Y., Zhu, Y., Cheang, P. Y S., Smith, P. R., Proc. 27th Ann. Int. Conf. IEEE EMBC, Shanghai, 2005.
  • Comparison of pulse interval in contact and non-contact photoplethysmography”, Hu, S*., Smith, P. R., Qiu, Y., Zhu, Y., ESC DIVISION RESEARCH, IEEE, Loughborough University 2005
  • “Induction of pulsatility in the venous system as a route to venous oxygen measurement”,  Smith, P. R., Chan, D., Crabtree, V. P., Hu, S., CNVD 2003, Conference paper and presentation, Praha, Czech Republic.
  • Development of a Protease Assay on a Miniaturized Flow System using Bioluminescence Detection Methods”, .Barrett, L.M., Miller, J.N., Hu, S.J., Palmer, D.A., French, M.T. and Murray, A., X Int’l Symposium on Luminescence Spectrometry-Detection Techniques in Flowing Streams-Quality Assurance and Applied Analysis, 2002, Granada, Spain.
  • Development and Application of A Novel, Compact Long-Wavelength Fluorescence Spectrometer”, Hu, S. J*., French, M.T., Palmer, P. A., Evens, M., and Miller, J. N., Pittcon Conf 50th (Orlando, USA 1999).

 

Proposal reviews

  • EPSRC Healthcare Impact Partnerships 2015
  • NEWFELPRO, Marie Curie FP7 – COFUND, 2014
  • i4i Challenge Awards Call 1 Stage 2, NIHR, DoH, Aug. 2012.
  • NIHR, DoH, Dec. 2010.
  • Heart Research, UK, NET20/10, Sep. 2010.
  • EPSRC: EP/G014396/1, June 2008.
  • British Council, Establishing Connections, PMI 2 Connect, Feb.2008.

Publication review

  • Over 100 publications including journal papers, scientific reports, peer review proceedings and patents have been reviewed with a range of interdisciplinary subjects including optoelectronics, photonics engineering, biomedical engineering, applied spectroscopy, electronics engineering, signal processing, mobile health, rehabilitation, sport physiological monitoring, health technology, microfluidic lab-on-chips etc. since 2004.