The following grant has been awarded by the AMR network:

Reducing antibiotic resistance, urinary tract infections and asymptomatic bacteriuria in kidney transplant recipients: effects of an exercise intervention.

Kidney transplant recipients are at a high risk of developing antibiotic resistance through repeated use of antibiotics for urinary tract infections (UTIs) and asymptomatic bacteriuria, with the added complications of surgery and immunosuppression. Interventions to reduce the prevalence of asymptomatic bacteriuria and risk of UTI in kidney transplant recipients would be particularly beneficial in reducing the development of antibiotic resistance in this high risk group.

This study will investigate the effects of an exercise intervention on the prevalence of asymptomatic bacteriuria and risk of urinary tract infection in kidney transplant recipients. The feasibility study will follow health outcomes and urine microbiology of kidney transplant recipients taking part in an eight week high intensity intermittent exercise intervention compared with a ‘control’ moderate intensity exercise group. This is part of a larger feasibility study based at the National Centre for Sport and Exercise Science East Midlands and School of Sport, Exercise and Health Sciences, Loughborough University and Leicester General Hospital funded by Heart Research UK.

Investigators: Lettie Bishop, Loughborough University; Emily Rousham, Loughborough University; Alice Smith, University Hospitals Leicester; Mathew Diggle, EMPATH,Nottingham University Hospitals NHS Trust.

For more information about the study, please contact Dr Lettie Bishop, School of Sport, Exercise and Health Sciences, Loughborough University.