28 Jun 2016
New Funding Awarded: A novel electrochemical nonlinear acoustic method for direct detection of bacterial infection
The following project has been awarded funding by the AMR network:
'A novel electrochemical nonlinear acoustic method for direct detection of bacterial infection'
Problem
Rapid point-of-care (POC) diagnostics is critical to early onset of ‘precision’ treatment, leading to improved patient outcome and controlled antimicrobial resistance. Delivering the accuracy of specialised lab-based tests with the desired speed, simplicity and low cost at the point of care is a technical challenge largely unaddressed till date.
Solution to Explore
A recently reported nonlinear acoustic technique, named Anharmonic Detection Technique (ADT), has demonstrated improved sensitivity and specificity in direct detection of bacteria with the potential for use in a rapid POC format [1]. This project aims to explore further enhancement of sensitivity and specificity of ADT under an additional electrode potential, leading to the development of a new and improved direct detection method e-ADT.
1. S. K. Ghosh et al, Biosensors and Bioelectronics, vol. 29 (1), pp. 145-50, 2011
Project Lead: Sourav Ghosh