Movement Insights Lab

Research

PhARaoH Study Participant

PhARaoH Study

Background

Hundreds of millions of people suffer every day from respiratory diseases. According to the latest World Health Organisation estimates, around 235 million people have asthma, 64 million people have chronic obstructive pulmonary disease (COPD) while millions have allergies and other, often underdiagnosed, chronic (long-term) respiratory diseases.

There are many benefits to leading a physically active lifestyle including reduced risks of cardiovascular disease and type 2 diabetes as well as improving mental health. There is a also a large body of evidence supporting important health benefits for people with respiratory disease. These benefits include reduced inflammation, fewer disease exacerbations and fewer reported sick days.

However, patients suffering with lung diseases often reduce their activity levels. This loss of physical activity is often cited as the most important problem perceived by lung disease patients. Ultimately, this reduction in physical activity leads to deconditioning which causes individuals to breathe more frequently when performing daily tasks. Consequently, lung disease patients who are inactive will experience more symptoms when they occasionally engage in activity. Due to the unpleasant nature of these symptoms, individuals will tend to avoid them, becoming even more inactive. This vicious cycle generally leads to a reduction in health-related quality of life.

 

Aims

The PhARaoH study aims to examine the roles of a range of lifestyle, social and psychological factors to better understand respiratory disease.

Of particular focus is the extent to which physical activity behaviours play a role in respiratory disease development and progression.

The results of this large observational study will be used to inform strategies to reduce the risk of respiratory disease.

 

Dataset

The PhARaoH study data collection has now finished and the information recorded is now contained within a large study dataset that can be used for scientific purposes upon request.

The dataset consists of a densely phenotyped sample of multi-ethnic adults collected from March to August 2014 (n=436; 139 COPD and 297 apparently healthy adults). The dataset captures behavioural, physical and psychosocial individual characteristics on individuals with and without a confirmed diagnosis of chronic obstructive pulmonary disease (COPD). The dataset includes seven day raw (100Hz) wrist-worn accelerometry, venous blood biomarkers and non-invasive point-of-care cardio-metabolic risk profiles.

All data were collected by trained researchers and participants were asked to attend the Respiratory Biomedical Research Unit, Glenfield Hospital, Leicestershire, UK for a one-off appointment of approximately 2-3 hours. Written informed consent was obtained from all participants provided before measures were completed. Participants were fully reimbursed for their travel and parking as part of their involvement in the study.

To make an enquiry about using this dataset, please click the button below and fill out the form.