Alloys-by-design: Multi-scale modelling of bone fracture PhD

Mechanical, Electrical and Manufacturing Engineering
Entry requirements:
2:1 +
Not available
Reference number:
UK/EU fees:
International fees:
Application deadline:
February 2018



in the UK for research quality

REF 2014


in the UK for Mechanical Engineering

The Complete University Guide 2018


of 2 Queen's Anniversary Prizes


Loughborough University is a top-ten rated university in England for research intensity (REF2014) and an outstanding 66% of the work of Loughborough’s academic staff who were eligible to be submitted to the REF was judged as ‘world-leading’ or ‘internationally excellent’, compared to a national average figure of 43%.

In choosing Loughborough for your research, you’ll work alongside academics who are leaders in their field. You will benefit from comprehensive support and guidance from our Doctoral College, including tailored careers advice, to help you succeed in your research and future career. 

Project detail

Bone fracture affects millions of people’s life worldwide. In UK alone, there are approximately more than 850,000 new fractures each year, and the estimated annual cost for bone fracture related treatment reached more than £2 billion. Traditional bone fracture treatment often uses internal/external fracture fixation or an assistive device. An emerging field of tissue engineering enables a new paradigm of treatments, using engineered tissue scaffolds and constructs for repair or replacement of the damaged tissue. In addition, demographic shift related to the aging population and accompanying degenerative bone diseases such as osteoporosis increase the risk of fracture significantly and result in a detrimental effect on surgical treatments of such fractures. Therefore, understanding the structure-function relationship of bone tissue in a wider population is key to the success for early diagnosis and prognosis of bone fracture and the subsequent healing process. 

The proposed project aims to develop a novel multi-scale, population-based approach to investigate damage and fracture mechanisms of bone tissue using the latest experimental and computational techniques, such as quantitative computer-tomography (q-CT), high-performance computing (HPC) and finite element analysis (FEA). The project is built upon previous research completed at Loughborough University, in collaboration with leading clinicians and scientists in the field with an aim to further advance the capacity and accuracy of in-silico models for various patient groups and loading conditions.

The successful candidate(s) will join the Mechanics of Advanced Materials Research Group (see below) and will participate in international research collaboration with partners in Ireland, Switzerland, USA and Australia (with potential secondments to them with duration of up to 6 or 12 months).


Primary supervisor: Dr Simin Li

Find out more

Entry requirements

Applicants should have, or expect to achieve, at least a 2:1 Honours degree (or equivalent) in Mechanical Engineering, Continuum Mechanics, Computer Science, Materials Science, Physics or a related subject. A relevant Master’s degree and/or experience in one or more of the following will be an advantage: Mechanical Engineering, Continuum Mechanics, Computer Science, Materials Science, Biomedical Engineering and Computational Biology.

All students must also meet the minimum English Language requirements.


Tuition fees cover the cost of your teaching, assessment and operating University facilities such as the library, IT equipment and other support services. University fees and charges can be paid in advance and there are several methods of payment, including online payments and payment by instalment. Special arrangements are made for payments by part-time students.

This is an open call for candidates who are sponsored or who have their own funding. If you do not have funding, you may still apply, however Institutional funding is not guaranteed. Outstanding candidates (UK/EU/International) without funding will be considered for funding opportunities which may become available in the School.

Fees and funding

How to apply

All applications should be made online. Under programme name select Mechanical and Manufacturing Engineering. Please quote reference number: SFSL130317