Loughborough University
Leicestershire, UK
LE11 3TU
+44 (0)1509 263171
Loughborough University

Centre for Biological Engineering

Plasma injection system: Reaching beyond the surface in plasma medicine applications

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The main two issues that plasma medicine needs to address before plasmas become widely accepted by the biomedical community are (1) selectivity, i.e. can plasma damage malignant cells whilst sparing healthy ones?; and (2) penetration, i.e. can plasma reach underneath the surface to infer its therapeutic value? Here we have focussed on the latter issue: penetration.

Given the non-equilibrium character of the chemistry developed in plasmas, their action is typically limited to the surface. While this is ideal for surface modification applications where we want to preserve the properties of the bulk material, most envisaged biomedical applications require plasma treatments to reach beyond the first monolayer of cells. Although plasma treatment penetration has not been studied in detail in the past, the literature has indirect evidence that suggests that plasma treatments weaken in tens of microns. Addressing this potential technology killer, the project undertook the development of a plasma injection system where a combination of a plasma jet and a needle-free liquid injector were operated synergistically to enable the penetration of plasma species inside a biological target.

Funding body


Project dates / duration

November 2012 - October 2012

Project team


Dr Felipe Iza: F.Iza@lboro.ac.uk, 01509 227077


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