Electronic and Electrical Engineering

The Photonics Engineering & Health Technology Research Group conducts research into the use of light for sensing & characterisation of dynamic systems of industrial and biological origin; The group collaborates towards biomedical engineering research projects and programmes with a number of national and international research groups and institutions; it has attained international appreciation for research into opto-physiological modelling to describe human physiological phenomena by effective capture of light trans-illuminating tissue. (www.pages.drexel.edu/~kmg462/currentresearch.html).

General research areas:

• Biomedical photonics engineering
• In-line biomedical signal and imaging processing
• Electronics and microelectronics for biomedical applications
• Biomedical Systems Integration
• Clinical risk assessment
• In-vitro diagnostics (IVD) instrumentation
• Non-invasive assessment
• Health technology Innovation

Specific research expertise:

• Tissue Optics, sensing and modelling
• Opto-physiological monitoring
• Plethysmography, pulse oximetry
• Opto-electronic probe configuration
• Biomedical engineering software design and implementation
• Point-of-care testing (POCT) photonic detection

Generic expertise in optical, electronic and software design at component and systems levels, combined with a team approach to problem solving, allows for a clear and rapid progression from fundamental research ideas to robust industrial prototypes. The majority of the Group's projects are pursued to the level of engineering implementations and further commercial exploitation.

• Opto-Physiological Monitoring
• OxiMap
• Non-Contact Pulse Oximetry
• Non-Contact measurement of aortic compliance with non-linear multi-wave opto-physiological image processing approach
• Non-invasive venous oximetry (VENOX)
• Imaging Photoplethysmography
• Opto-physiological Modelling of Pulse Oximetry
• Multi-plex point of care testing instrumentation

 

 

The Queen Mary, University of London

 

Collaboration on:
Non-contact measurement of aortic compliance

 

Shanghai Jiao Tong University

 

 

Collaboration on:
Biomedical monitoring and signal processing

 

University Hospitals of Leicester

 

Collaboration on:
Non-invasive vascular assessment and clinical study

Tsinghua University, Beijing

 

 

Collaboration on:
Opto-electrical sensor for brain computer interface

 

Shanghai Upper Bio-Tech (Group) Co.

 

 

Collaboration on:
In-vitro diagnostics (IVD) point-of-care testing (POCT) instrumentation

Selected publications

• Shi, P., Hu, S. and Zhu, Y., ''A Preliminary Attempt to Understand Compatibility of Photoplethysmographic Pulse Rate Variability with Electrocardiogramic Heart Rate Variability'', Journal of Medical and Biological Engineering, 2008, 28(4):   866- 871 .
• Xin, S., Hou, W., Qian, J., Hu, S., Crabtree, V.P. and  Smith, P. R., ''Study on blood pulse photoplethysmography signal on toe under different body posture and lower limb height'', Journal of University of Shanghai for Science and Technology, 2008, 30(5): 173-180 .
• Zheng, J., Hu, S., Xin, S. and Crabtree, V., “Effect of postural changes on lower limb blood volume, detected with non-invasive photoplethysmography”, Journal of Medical Engineering and Technology, 2008,32(5) : 358 – 364.
• Shi, P., Zhu, Y., Allen, J. and Hu, S., ''Analysis of Pulse Rate Variability Derived from Photoplethysmography with the Combination of Lagged Poincare Plots and Spectral Characteristics'', Medical Engineering and Physics, 2009,31(7): 866-871.
• Zhao, H., Qiu, Y., Hu, S. and Zhu, Y., “ Detrended Fluctuation Analysis of Pulse Rate Variability Signals of Coronary Patients”, Space Medicine and Medical Engineering,, 2008,20(6): 455-457.
• Echiadis, A. S., Crabtree, V. P., Bence, J., Hadjinikolaou, L., Alexiou, C., Spyt, T. J. and Hu, S., “Non-invasive measurement of peripheral venous oxygen saturation using a new venous oximetry method: evaluation during bypass in heart surgery”, Physiological Measurement , 2007,28(8): 897–911.
• Xin, S., Hu, S., Crabtree, V. P., Zheng, J., Azorin-Peris, V.  Echiadis, A. S and Smith, P. R.,  “Investigation of blood pulse PPG signal regulation on toe effect of body posture and lower limb height ”, Journal of Zhejiang University, 2007,8(6) : 916-920.
• Azorin-Peris, V.,  Hu, S. and Smith, P. R., “A Monte Carlo Platform for the Optical Modelling of Pulse Oximetry”, Proceedings SPIE, 2007, 6446, 64460T1-6.
• Cai, Y., Qiu, Y.,H., Wei, L., Zhang, W., Wang, Z., Jiang, D., Hu, S., Smith, P. R. and Crabtree, V. P., Tong, S. B., Thankor, N., Zhu, Y., “Complex character analysis of Heart Rate Variability following brain asphyxia”, Medical Engineering & Physics , 2006,28(4) : 297–303.
• Hu, S.  “A Multiplex fluorescence and Absorbance Detector”, Chinese patent: (CN101236153), Priority date: 06/08/2008
• Hu , S., Echiadis., A. S. and Chouliaras, V. “Real-time Vascular Imaging,  International Patent, (PCT/GB2008/003042), Priority date: 08/09/2007 2007.