Loughborough University
Leicestershire, UK
LE11 3TU
+44 (0)1509 222222
Loughborough University

Chemical Engineering

News and Events

Oxford AHSN

September 14

Four shortlisted in our search for best public-private collaboration

The Oxford AHSN aims to break down traditional organisational boundaries and bring the NHS, universities, science and business closer together. To that end we have been inviting nominations for a new award acknowledging effective partnerships between the public sector and industry. A shortlist has now been drawn up and the winners will be announced at the OBN Annual Awards night on 2 October (http://www.obn.org.uk/events/obn-annual-awards-dinner/ ).

 

The shortlisted public-private collaborations are (in no particular order):

Who?

Buckinghamshire Healthcare NHS Trust, University of Reading and University of Loughborough

What?

Development of microcapillary film offering low-cost rapid testing of multiple biomarkers for a wide range of point-of-care diagnostic applications including acute cardiovascular disease and rapid microbial identification. The start-up company Capillary Film Technology Ltd (www.capfilmtech.com ) has received funding from private investors, SBRI (www.sbrihealthcare.co.uk ) and other sources.

 

University of Reading,   University of Loughborough and Buckinghamshire Healthcare NHS Trust

Introduction

An on-going   collaboration between manufacturing and diagnostics experts, academics at   Cambridge, Reading and Loughborough, and clinicians, have together developed   a new ‘affordable microfluidic’ platform that offers low cost rapid testing   of multiple biomarkers for a broad range of point-of-care diagnostic   applications, ranging from acute cardiovascular disease through infection to   rapid microbial identification. Microcapillary film (MCF) can be used to   sensitively measure up to 10 biomarkers in a single small biological sample   such as blood.

Background

Although originally   invented by Cambridge University academics Mackley and Hallmark, producing   MCF from fluoropolymers with unique optical properties needed manufacturing   expertise from Patrick Hester at UK manufacturing SME and extrusion experts   Lamina Dielectrics Ltd. The concept of exploiting the low cost and unique   properties of fluoropolymer MCF for microfluidic diagnostics was invented by   Edwards and Reis whilst Cambridge postdocs and subsequently developed as   academics at Reading and Loughborough. In 2012 they joined forces with   Patrick Hester and Lamina to found start up Capillary Film Technology Ltd   (CFT).

Public and private funding

A combination of   private investment and recently a SBRI healthcare feasibility contract to   CFT, with research council grants and graduate student expertise at   universities of Reading and Loughborough, has generated data essential for   technology uptake and is now driving development of next generation of point   of care diagnostic products.

Clinical input

To complete the   partnership, on-going clinical input is provided through AHSN meetings to   inform biomarker panel selection. For example CFT have recently discussed   clinical evaluation of rapid cardiovascular biomarker tests with cardiologist   Dr Clifford.

List of participants/contacts:

Present/current private   partners:

CFT Ltd www.capfilmtech.com  

CEO Dr Lee Smith lee.smith@capfilmtech.com  

Lamina Dielectrics Ltd   www. www.lamina.uk.com   

Patrick Hester: Patrick.Hester@lamina.uk.com  

Present/current public partners:

University of Reading:   Reading School of Pharmacy, Dr Al Edwards a.d.edwards@reading.ac.uk  

University of   Loughborough: Chemical Engineering, Dr Nuno Reis N.M.Reis@lboro.ac.uk

Buckinghamshire   Healthcare NHS Trust: Dr Piers Clifford Piers.Clifford@buckshealthcare.nhs.uk  

Past public partners:

University of   Cambridge: Chemical Engineering, Professor Malcolm Mackley (malcolmmackley@gmail.com)   and Dr Bart Hallmark bh206@hermes.cam.ac.uk  

 

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Department of Chemical Engineering
Loughborough University
LE11 3TU
UK

+44 (0)1509 222 533